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mst IsUsedBy is a simple, but very useful free tool. It allows you determine what process opened a particular file. You only have to drag the file to the IsUsedBy window. This can be useful if Windows doesn’t allow you to move or delete a file.
Rate this tool: 
(3 votes, average: 2.67 out of 5)
(3 votes, average: 2.67 out of 5)
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The number of ‘free’ tools (process exp, process mon, to name a few) that can ID file-process connections seems to be growing every month. One would think MS would vamp up TaskMgr to do the same. Is there one process tool head-n-shoulders about the rest?
what? there’s already the excellent ‘unlocker’ who really does the job.